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They concluded that switching from one generic to another is fine ( JAMA Internal Medicine, Feb. I was feeling so crappy before starting, I didn't want to take any chances Just today, I picked up what I thought was my Synthroid refill to find out it was generic, very upset, 90 days worth, can't return it, most likely …. T3 is about 3-4 times more powerful than T4 (depending on which study you look at) Lower-cost generic is available Ratings & Reviews Levothyroxine has an average rating of 5. 6k views Answered >2 years ago Thank 1 thank View 1 more answer A member asked:. Introduction Levothyroxine monotherapy (Synthroid® or multiple generic levothyroxine [GL] formulations) is standard treatment for hypothyroidism. At least I have heard it several times I've read that pretty much generic is plus/minus 7mcg while Synthroid would likely be plus/minus 5mcg (random numbers). Brand name Synthroid and generic levothyroxine are chemically identical hormones, l-thyroxine. 2 out of 10 from a total of 805 ratings on Drugs. Most generic medications are more or less the same. Generic Levothyroxine Ericamegan My endo recommended that I take Synthroid instead of the generic. I've also read that synthroid comes from one company while generics can come from a multitude of companies. She said this is one of the only drugs she really recommends not to take the generic. I was feeling so crappy before starting, I didn't want to take any chances The FDA maintains that generic levothyroxine is the same as brand name Synthroid. She said she has seen some patients that don't absorb the generic as well. Generic: What the Research Says According to a presentation at the annual meeting of the American Association of Clinical Endocrinologists in 2017, Synthroid was associated with significantly better thyroid-stimulating hormone (TSH) lab results than generic levothyroxine. Our objective was to compare effectiveness (as measured by achievement of thyroid-stimulating hormone [TSH] levels) and economic outcomes of Synthroid vs. Except with Levothyroxine/Synthroid. Your story is not unusual, however Adults aged 18 years or older were included if they filled a generic levothyroxine prescription between January 1, 2008, and June 30, 2019, and had a stable drug dose, the same drug manufacturer, and a normal TSH level (0. So the range of variability between generics and "branded" levothyroxine is minimal as far as the active ingredients. Back in 2007 the fda tightened their standards for levothyroxine since they classify it as a drug with a narrow therapeutic index. Levothyroxine is also available under other brand names, including Tirosint® and Levoxyl® Brand vs. 4 mIU/L) for at least 3 months before either continuing to take the same product or switching among generic levothyroxine products (index date).. Synthroid and Levothyroxine are both considered T4 only thyroid medications which means that they contain the bio-identical thyroid hormone Thyroxine. Any one of multiple GLs in patients with hypothyroidism. FDA scientists recently collaborated with endocrinologists from Yale and the Mayo Clinic. Synthroid releases it's TSH over a period of 16-18 hours so when it's reaching the period where it's not in your bloodstream any more, it's time for your next morning dose. To the best of my knowledge, the reason you must have your blood tested if the brand of levothyroxine you are taking changes is because there is a 5% plus or minus difference in the amount of medication absorbed between manufacturers Synthroid vs. I was prescribed generic levo but I know my mom (longtime hypo) made me go get synthroid prescribed the next week lol GE. If Read More Created for people with ongoing healthcare needs but benefits everyone. If you search the orange book you can get more information Synthroid vs. You get the same concentration of medication and such. The inert ingredients vary, but that's trivial. Methods Data for this retrospective. I have found, and my doctor reached the same conclusion, that levothyroxine releases all of the TSH over a period of 6-8 hours, then you go 16-18 hours with no TSH. There can be subtle differences from manufacturer to manufacturer in the actual dosage. Liothyronine, on the other hand, contains the most potent thyroid hormone which is known as T3 or triiodothyronine.